Despite treatment with agents that enhance beta-cell function and insulin action, reduction in beta-cell mass is relentless in patients with insulin resistance and type 2 diabetes mellitus.Insulin resistance is characterized by impaired signaling through the insulin/insulin receptor/insulin receptor substrate/PI-3K/Akt pathway, leading to elevation
Herpes zoster (HZ), caused by reactivation of varicella-zoster virus (VZV), is an uncommon cause of rash in pediatrics, which can lead to concerns of an underlying immunodeficiency.We reviewed studies on HZ in pediatric patients.The diagnosis of HZ can usually be established based on clinical and epidemiological features.HZ is associated with T-cel
BackgroundSurveys are an effective method for collecting a large quantity of data.However, incomplete responses to these surveys can affect the validity of the studies and introduce bias.Recent studies have suggested that monetary incentives may increase survey response rates.We intended to perform a systematic review and meta-analysis of randomize
FGFR1 is a key member of the fibroblast growth factor receptor family, mediating critical signaling pathways such as RAS-MAPK and PI3K-AKT.which are integral to regulating essential cellular processes, including proliferation, differentiation, and survival.Alterations napoleon concealer in FGFR1 can lead to constitutive activation of signaling path